Nicorandil: ulcer and location

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Insights in the mechanisms underlying the anti-ulcer activity of nicorandil.

This study was conducted to investigate possible mechanisms underlying the gastroprotective effect of nicorandil on experimentally-induced gastric lesions in rats. The rats were randomly assigned to vehicle (saline or tween 80), nicorandil (2 mg/kg), glibenclamide (2 mg/kg), nicorandil plus glibenclamide- and cimetidine (50 mg/kg)-pretreated groups, in addition to the non-stressed control group...

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ژورنال

عنوان ژورنال: The Journal of Laryngology & Otology

سال: 2014

ISSN: 0022-2151,1748-5460

DOI: 10.1017/s0022215114000516